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Nuclear Stress Test What is it?

 A nuclear stress test is a common test that doctors use to diagnose coronary artery disease or to determine if there is a lack of blood flow to your heart as it relates to previously known blockages. This test uses a radioisotope injected into the blood stream during a normal resting state and then a second dose during the stress test. Two images are taken of your heart with a Gamma camera within two hours of having each injection.  A comparison is made between the two images which determines whether or not you have significant blockages in the heart arteries which are affecting the blood flow to the heart. 

What should I expect? You will be mailed or given detailed instructions with the specifics about not eating or drinking prior to the test and about bringing your medications and a snack with you.  In general, do not eat or drink for 6 hours before the test.  DO NOT HAVE items that contain caffeine, which is found in coffee, tea, sodas, chocolate, and some over-the-counter pain relievers.  Also, be sure to ask your doctor about any medicines you are taking and whether you should stop taking them before the test.  There are certain medications that can interfere with testing and should be held 24 to 48 hours prior to testing. The nuclear stress test takes between 4 and 5 hours to complete.The day of the test, you will initially have your medication bottles reviewed, discuss the test, sign an informed consent, and have your height and weight recorded.  You will have an IV started and a resting injection of the radioisotope (nuclear medicine) will be administered.  It is not a dye and will not make you feel differently.  After that, you will be allowed to take your medications if they do not interfere with the test, and eat breakfast.  YOU CAN NOT HAVE CAFFEINE UNTIL TESTING IS COMPLETED. After about 45 minutes, a resting image is taken.  You will either sit up or lie down on a Gamma camera and have a 15 minute scan of your heart.  You must remain very still during this image or it will have to be repeated. 

 
Then you will have a 30 minute to 1 hour wait before the stress test is performed.  You will be connected to a 12 lead EKG machine for the stress test whether you walk on the treadmill or have a pharmacological (or chemical) stress test. Alcohol is used to clean the areas of your skin where the electrodes will be placed.  The alcohol may feel cold.  Next, electrodes will be placed on your chest. The electrodes are attached to an electrocardiograph machine, which records your heart’s electrical activity. A healthy person’s electrocardiogram has a certain pattern, and changes in that pattern can tell doctors if there is a problem with your heart. You will also wear a blood pressure cuff around your arm, which will be used to watch your blood pressure during the test. Before the stress test, your blood pressure and pulse will be checked. They will also record your heart’s electrical activity before you start exercising (called a resting EKG).  If you have the exercise test, you will walk on a treadmill to achieve a target heart rate.  Once that heart rate is achieved a second dose (or stress dose) of the radioisotope (nuclear medicine) will be injected. 

 
You will need to walk at least one minute following the injection to let it circulate before stopping.  The nurse with you during the stress test will increase the speed and slope of the treadmill every third minute. He or she will look for changes in the electrocardiogram patterns and blood pressure levels, which may tell doctors that your heart is not getting enough oxygen. Other signs of coronary artery disease include chest pain or unusual shortness of breath while you are exercising. If your doctor would rather you not exercise, a medication can be administered with you lying on a stretcher to achieve the stress test.  If you are not able to walk safely on the treadmill, have certain ekg patterns, a pacemaker, or a defibrillator it may be best to do the chemical stress test as opposed to exercise.    If you try the treadmill and cannot achieve the target heart rate, then a chemical stress test will be necessary. The radioisotope (nuclear medicine) is administered during that chemical stress test. At the end of the test, you will have a cool-down phase and be asked to drink something cold prior to the last scan of your heart.  That scan will be on the same Gamma camera you were on at the beginning of the morning. 

After the test is completely over, you may eat, drink, and take all medications including those that may have been held prior to testing.   You can go back to your normal activities. 

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